1. Appearance: Describes the appearance of Semaglutide powder or solution, including color and physical form.

2. Nominal Content: This refers to the percentage of the active ingredient in Semaglutide. The COA typically lists the nominal content to ensure it matches the value stated by the manufacturer.

3. Purity: Includes the chemical purity of Semaglutide, usually expressed as a percentage. This can encompass the content of major components as well as any impurities.

4. Moisture Content: Describes the amount of moisture in Semaglutide. Moisture content is critical for drug stability and storage.

5. Heavy Metal Content: Evaluates the presence of heavy metals (such as lead, mercury, cadmium) in Semaglutide. These heavy metals are harmful to humans, so their concentration in the drug must be low.

6. Microbial Limits: Indicates the limits for microorganisms (e.g., bacteria, fungi, E. coli) allowed in Semaglutide.

7. Solubility: Describes the solubility of Semaglutide in specific solvents. Solubility can impact drug suitability and availability.

8. pH Value: Measures the pH of Semaglutide solution. pH can affect drug stability and biological activity.

9. Specific Rotation: If Semaglutide is an optical isomer (stereoisomer), specific rotation may be used to describe its optical activity.

10. Other Parameters: Depending on the manufacturer and regulatory requirements, the COA may include other important parameters, such as the content of related substances, specific impurities, etc.

These parameters may vary depending on the manufacturer, batch, and regulatory requirements. The purpose of the COA is to ensure that Semaglutide meets relevant regulations and standards in terms of quality and purity and is safe and effective for clinical use. It is important to carefully read and understand the relevant COA before using Semaglutide.